Arsenal v Bournemouth Arsenal defender Jurrien Timber is available to make his return from a serious knee injury against Bournemouth.
The Dutchman has been out of action since suffering a torn ACL on the opening weekend of the season.
Bournemouth's Milos Kerkez serves the second game of a three-match ban.
Antoine Semenyo is a doubt because of a knee injury, while Luis Sinisterra and Marcus Tavernier will likely remain out. Brentford v Fulham Neal Maupay is available for Brentford, having been ineligible to face parent club Everton last weekend.
Aaron Hickey, Rico Henry, Ben Mee and Joshua Dasilva are all long-term absentees.
Fulham's Harrison Reed could be out after suffering a knock against Crystal Palace.
Tosin Adarabioyo isn't injured but he was omitted from the matchday squad last weekend amid speculation on his future at the club.
Burnley v Newcastle Burnley's Luca Koleosho may be in contention for the first time since having knee surgery in December.
Nathan Redmond, Aaron Ramsey and Jordan Beyer all remain long-term absentees.
Newcastle's Fabian Schar is likely to be ruled out for the rest of the season with a hamstring injury.
Joelinton, Miguel Almiron and Nick Pope have all returned to training and could be available this weekend but full-back Kieran Trippier is not yet ready to return.
Sheffield United v Nottingham Forest James McAtee is fit and available for Sheffield United after he missed the defeat by Newcastle with a groin issue.
Rhian Brewster, Rhys Norrington-Davies and Tom Davies are nearing returns but are unlikely to feature this season.
Nottingham Forest defenders Willy Boly and Murillo have both recovered from minor knocks sustained against Manchester City last weekend.
Striker Taiwo Awoniyi could make his comeback from a thigh problem, while Neco Williams will also be assessed.
Man City v Wolves Manchester City welcome back Phil Foden and Ruben Dias, both of whom missed their last game through illness.
Goalkeeper Ederson should also be available despite being forced off last weekend with a shoulder issue.
Wolves head coach Gary O'Neil serves a one-match touchline ban following his angry reaction to a disallowed goal against West Ham last month.
Tommy Doyle, whose his loan from City will be made permanent this summer, is ineligible to face his parent club.
Jean-Ricner Bellegarde, Pedro Neto and Santiago Bueno could return to contention after resuming training, though this game may come too soon for Noha Lemina.
Brighton v v Aston Villa Adam Lallana is the latest addition to Brighton's lengthy injury list.
James Milner, Tariq Lamptey, Pervis Estupinan, Evan Ferguson, Jack Hinshelwood, Solly March, Jan Paul van Hecke and Kauro Mitoma all remain out.
Aston Villa may have goalkeeper Emiliano Martinez available again following a hamstring issue.
Alex Moreno and Youri Tielemans will also be assessed, while Nicolo Zaniolo returned from injury as a substitute against Olympiacos on Thursday.
Chelsea v West Ham Chelsea are hoping Levi Colwill and Christopher Nkunku could return from respective toe and hamstring injuries.
The Blues were without 14 players for the midweek win over Tottenham, including Thiago Silva, Enzo Fernandez and Ben Chilwell.
West Ham's Konstantinos Mavropanos could return after missing the last three matches.
Fellow defender Nayef Aguerd remains sidelined but the Hammers have no fresh injury problems.
Liverpool v Tottenham Hotspur Liverpool captain Virgil van Dijk is doubtful through injury, while this match comes too soon for Diogo Jota.
Joel Matip and Thiago Alcantara remain long-term absentees but Conor Bradley is back in contention.
Tottenham boss Ange Postecoglou says there was no "significant" injury news following Thursday's defeat at Chelsea but added that several players are are "feeling the effects of the game".
Timo Werner and Ben Davies are among six players who remain sidelined.
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