Brentford V Chelsea Brentford defender Ben Mee is out for the season after fracturing his ankle at West Ham on Monday.
Aaron Hickey, who has not played since October, has had a setback in his recovery from a hamstring injury.
Chelsea hope Thiago Silva will be fit after a groin injury and Marc Cucurella also faces a late fitness test.
Christopher Nkunku faces a few more weeks out with Benoit Badiashile and Romeo Lavia among those also still sidelined.
Everton V West Ham Everton pair Idrissa Gueye and Amadou Onana will both be assessed after they sustained groin injuries in the draw at Brighton & Hove Albion last weekend.
Andre Gomes has returned to training, although Lewis Dobbin and Arnaut Danjuma remain out.
West Ham United's only absentee is Maxwel Cornet, who will miss several weeks with a hamstring injury.
Kalvin Phillips is available after missing the win against Brentford through suspension.
Fulham V Brighton
Fulham midfielder Joao Palhinha serves the second game of a two-match suspension.
Willian is fit again, with Raul Jimenez, who has a hamstring problem, the only current injury absentee.
Brighton midfielder Billy Gilmour is banned after his red card against Everton last week.
Kaoru Mitoma is set to miss the rest of the season but Evan Ferguson, Joel Veltman and Tariq Lamptey could return after being unavailable in midweek.
Newcastle V Wolves Newcastle defender Sven Botman could return after being rested for the midweek FA Cup win.
Elliot Anderson will be pushing for more game time after his return from a back injury but Matt Targett is not yet fit after a hamstring problem.
Wolves forward Hwang Hee-chan is out with the hamstring injury he suffered in midweek.
Matheus Cunha remains sidelined but Joao Gomes should be fit despite suffering cramp in Wednesday's win.
Nottingham Forest V Liverpool Nottingham Forest boss Nuno Espirito Santo says Chris Wood, Ibrahim Sangare and Willy Boly are nearing returns, though it is not clear if any of them will be available on Saturday.
Ola Aina and Nuno Tavares remain sidelined.
Darwin Nunez and Dominik Szoboszlai could return for Liverpool after resuming training on Thursday.
Andy Robertson and Wataru Endo are due to train on Friday and may also come back into contention.
Nine other players are ruled out, including Mohamed Salah, Alisson and Trent Alexander-Arnold. Tottenham V Crystal Palace Tottenham Hotspur forward Richarlison will miss up to four weeks through injury, while Pedro Porro remains out.
Destiny Udogie has returned to training but Ryan Sessegnon has undergone surgery on a hamstring injury sustained in an under-23 match.
Crystal Palace forward Eberechi Eze is back in contention following four games out, while Will Hughes and Joachim Andersen are also available.
Marc Guehi is out for an extended period following knee surgery.
Luton Town V Aston Villa Luton defender Issa Kabore is back in contention after being ineligible against parent club Manchester City.
Amari'i Bell is doubtful after injuring his hamstring in the midweek defeat, while Joe Johnson is not fit to start following illness. Elijah Adebayo, Albert Sambi Lokonga and Gabriel Osho are ruled out.
Aston Villa defender Pau Torres is fit, having been withdrawn as a precaution at half-time against Nottingham Forest because of a minor issue.
Ezri Konsa is back in contention after missing four matches with a knee injury, but this game comes too soon for Jhon Duran, who remains sidelined along with long-term absentees Tyrone Mings, Emi Buendia and Boubacar Kamara.
Burnley V Bournemouth Burnley midfielder Josh Brownhill serves a one-match suspension after he was sent off against Crystal Palace.
Jordan Beyer is progressing well following a hamstring issue but his return has not been confirmed.
Bournemouth will make a late decision on Dominic Solanke, who is yet to resume training following a clear MRI scan on a knee injury on Tuesday.
Enes Unal is back in contention following a shoulder problem but Lloyd Kelly remains out.
Man City V Man United Manchester City winger Jack Grealish is ruled out after injuring his groin in Tuesday's FA Cup win at Luton.
Josko Gvardiol is nearing a return from an ankle problem but this game may come too soon for him.
Manchester United manager Ten Hag does not expect any of his players to return from injury on Sunday.
Bruno Fernandes and Raphael Varane both completed Wednesday's win at Nottingham Forest despite fitness issues and are again expected to be available.
